4-Cyano-2-(trifluoromethyl)phenol, 5-Cyano-2-hydroxybenzotrifluoride
4-Hydroxy-3-(trifluoromethyl)benzonitrile
CAS: 124811-71-8
Molecular Formula: C8H4F3NO
4-Cyano-2-(trifluoromethyl)phenol, 5-Cyano-2-hydroxybenzotrifluoride - Names and Identifiers
4-Cyano-2-(trifluoromethyl)phenol, 5-Cyano-2-hydroxybenzotrifluoride - Physico-chemical Properties
| Molecular Formula | C8H4F3NO |
| Molar Mass | 187.12 |
| Density | 1.44±0.1 g/cm3(Predicted) |
| Melting Point | 171-175℃ |
| Boling Point | 256.0±40.0 °C(Predicted) |
| Flash Point | 108.6°C |
| Water Solubility | Insoluble in water. |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.00983mmHg at 25°C |
| Appearance | White to Brown Powder |
| Color | Pale Brown |
| pKa | 5.85±0.43(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.495 |
| MDL | MFCD06797882 |
4-Cyano-2-(trifluoromethyl)phenol, 5-Cyano-2-hydroxybenzotrifluoride - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Note | Irritant |
4-Cyano-2-(trifluoromethyl)phenol, 5-Cyano-2-hydroxybenzotrifluoride - Introduction
4-Hydroxy-3-trifluoromethylbenzonitrile (-) is an organic compound with the chemical formula C8H4F3NO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 4-hydroxy-3-trifluoromethylbenzonitrile is a colorless to pale yellow solid.
-Solubility: It does not dissolve in water, but has better solubility in organic solvents.
-Melting point: Its melting point is about 107-109 degrees Celsius.
Use:
-4-hydroxy-3-trifluoromethylbenzonitrile can be used as an important intermediate in organic synthesis and used in the synthesis of other organic compounds.
-It can also be applied to certain research and synthesis processes in the field of medicine.
Method:
The preparation method of 4-hydroxy-3-trifluoromethylbenzonitrile can be achieved by the following steps:
1. reacting benzonitrile with trifluoromethyl alcohol to give 3-trifluoromethylbenzonitrile.
2. 3-trifluoromethylbenzonitrile is reacted with sodium hydroxide (NaOH) to obtain 4-hydroxy-3-trifluoromethylbenzonitrile.
Safety Information:
Regarding the safety of 4-hydroxy-3-trifluoromethylbenzonitrile, the following are some basic safety information:
-This compound may be irritating to the skin, eyes and respiratory tract.
-When using or handling, follow appropriate safety practices, including wearing personal protective equipment such as gloves, safety glasses and protective face shields.
-Avoid inhaling its vapors or dust, avoid contact with skin and eyes.
-In case of inadvertent contact, immediately flush the infected area with plenty of water and seek medical help.
it should be noted that the above information is only a general description of 4-hydroxy-3-trifluoromethylbenzonitrile, and the specific properties, uses and safety information may need to be further understood and confirmed according to the specific situation. Laboratory safety and professional guidance should be strictly followed when using chemicals.
Nature:
-Appearance: 4-hydroxy-3-trifluoromethylbenzonitrile is a colorless to pale yellow solid.
-Solubility: It does not dissolve in water, but has better solubility in organic solvents.
-Melting point: Its melting point is about 107-109 degrees Celsius.
Use:
-4-hydroxy-3-trifluoromethylbenzonitrile can be used as an important intermediate in organic synthesis and used in the synthesis of other organic compounds.
-It can also be applied to certain research and synthesis processes in the field of medicine.
Method:
The preparation method of 4-hydroxy-3-trifluoromethylbenzonitrile can be achieved by the following steps:
1. reacting benzonitrile with trifluoromethyl alcohol to give 3-trifluoromethylbenzonitrile.
2. 3-trifluoromethylbenzonitrile is reacted with sodium hydroxide (NaOH) to obtain 4-hydroxy-3-trifluoromethylbenzonitrile.
Safety Information:
Regarding the safety of 4-hydroxy-3-trifluoromethylbenzonitrile, the following are some basic safety information:
-This compound may be irritating to the skin, eyes and respiratory tract.
-When using or handling, follow appropriate safety practices, including wearing personal protective equipment such as gloves, safety glasses and protective face shields.
-Avoid inhaling its vapors or dust, avoid contact with skin and eyes.
-In case of inadvertent contact, immediately flush the infected area with plenty of water and seek medical help.
it should be noted that the above information is only a general description of 4-hydroxy-3-trifluoromethylbenzonitrile, and the specific properties, uses and safety information may need to be further understood and confirmed according to the specific situation. Laboratory safety and professional guidance should be strictly followed when using chemicals.
Last Update：2024-04-09 21:54:55
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Product Name: 4-Hydroxy-3-(trifluoromethyl)benzonitrile Visit Supplier Webpage Request for quotation
CAS: 124811-71-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 124811-71-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
4-Cyano-2-(trifluoromethyl)phenol, 5-Cyano-2-hydroxybenzotrifluoride
ethyl 2.4-dioxo-4-M-tolylbutanoate
ethyl 2.4-dioxo-4-M-tolylbutanoate